Isoniazid Level (+N-Acetyl-Isoniazid)

Container: container
Turnaround time: 7 working days
Description: Isoniazid Level (+N-Acetyl-Isoniazid)
Preparation:

Samples must be taken as per the tube manufacturer's processing instructions.

Vessels and Containers:

Fluoride Oxalate (Fx) tube

Sample requirements:

Approx 1-2ml of blood taken in Fluoride Oxalate (Fx) tube

Interference:

The results obtained for this assay depend on adequate identification, collection, transport, storage and processing of samples. To avoid incorrect results, it is therefore necessary to take care during these steps and to carefully follow the instructions. Results obtained must be interpreted taking into consideration the clinical data and other laboratory tests.

How result is reported:

Quantitative

Important Information: Website updated: January 2024
Comments: Internal test code: ISDL
Transportation and Handling: Transport at room temperature.
Special Precautions: Samples should be transported as quickly as possible to the department so sample stability is not compromised. Samples MUST be sent as whole blood (unspun and unseparated) so that they can be referred within 5 days of being taken. Timing of samples: It is recommended a post dose sample, taken 2 hours after the end of administration (and/or 6 hours if monitoring absorption) Clinical Summary is required on the sample request
Time limits for requesting additional examinations: Samples are not stored within the Virology department as the whole sample is sent to the reference laboratory.
Reference Lab Description: Regional Antimicrobial Reference Lab, Bristol

Reference Range

Isoniazid Post doe: 3.0 - 5.0 mg/L;
N-Acetyl Isoniazid Post dose: N/A (indicator of rate of isoniazid metabolism to the inactive form).